Roma have been drawn against either Naftan Novopolotsk of Belarus or Gent of Belgium in the third qualifying round of the UEFA Europa League.
Naftan have a 2-1 advantage over Gent going into next Thursday's second qualifying round second leg tie away from home.
Roma, seeded in Group 1 for the draw, qualified for the competition, which replaces the UEFA Cup, by finishing a disappointing sixth in last season's Serie A.
The Giallorossi will travel away for the first leg on Thursday 30 July, with the home leg in Rome on Thursday 6 August.
Naftan qualified for the inaugural Europa League tournament by winning the Belarusian Cup for the first time in their history last season, while Gent reached this stage by finishing fourth in the Belgian Jupiler Pro League.
The winners of the 35 third qualifying round encounters will go into the draw for the play-off round on 7 August, with ties on 20 and 27 August. That final qualifying stage will include losing teams from the UEFA Champions League third qualifying round, plus domestic cup winners and other teams from Europe's strongest football nations, including Italy's other two Europa League entrants, Genoa and Lazio.
The winners of the play-off round will then reach the group stage, which will see 48 teams play in 12 four-team groups between September and December before a knockout stage begins next February featuring additional teams from the Champions League group stage.
The final is scheduled to be played in Hamburg on Wednesday 12 May, 2010.
UEFA Europa League 2009-10
Third Qualifying Round
First leg: 30 July - Second leg: 6 August
Helsingborgs (SWE) 2-1 Sarajevo (BIH) / Sarajevo p2-1 Helsingborgs
Fredrikstad (NOR) 1-6 Lech Poznan (POL) / Lech Poznan 1-2 Fredrikstad
Rijeka (CRO) 1-2 Metalist Kharkiv (UKR) / Metalist Kharkiv 2-0 Rijeka
Roma (ITA) 3-1 Gent (BEL) / Gent 1-7 Roma
Vaslui (ROU) 2-0 Omonia (CYP) / Omonia 1-1 Vaslui
Slavija Sarajevo (BIH) 0-2 Kosice (SVK) / Kosice 3-1 Slavija Sarajevo
Goteborg (SWE) 1-3 Hapoel Tel-Aviv (ISR) / Hapoel Tel-Aviv 1-1 Goteborg
PSV Eindhoven (NED) 1-0 Cherno More Varna (BUL) / Cherno More Varna 0-1 PSV Eindhoven
Metalurh Donetsk (UKR) 2-0 Ljubljana (SVN) / Ljubljana 0-3 Metalurh Donetsk
Valerenga (NOR) 1-2 PAOK (GRE) / PAOK a0-1 Valerenga
Rapid Vienna (AUT) 2-1 APOP-Kinyras Peyias (CYP) / APOP-Kinyras Peyias 2-2 Rapid Vienna
Honka Espoo (FIN) 0-1 Qarabag (AZE) / Qarabag 2-1 Honka Espoo
Vaduz (LIE) 0-1 Slovan Liberec (CZE) / Slovan Liberec 2-0 Vaduz
St Patrick's Athletic (IRL) 1-0 Krylya Sovetov Samara (RUS) / Krylya Sovetov Samara 3-2a St Patrick's Athletic
Randers (DEN) 0-4 Hamburg (GER) / Hamburg 0-1 Randers
Tromso (NOR) 2-1 Slaven Koprivnica (CRO) / Slaven Koprivnica 0-2 Tromso
Brondby (DEN) 1-1 Legia Warszawa (POL) / Legia Warszawa 2-2a Brondby
Vojvodina (SRB) 1-1 Austria Vienna (AUT) / Austria Vienna 4-2 Vojvodina
CSKA Sofia (BUL) 1-0 Derry City (IRL) / Derry City 1-1 CSKA Sofia
Steaua Bucharest (ROU) 3-0 Motherwell (SCO) / Motherwell 1-3 Steaua Bucharest
Zilina (SVK) 1-1 Hajduk Split (CRO) / Hajduk Split 0-1 Zilina
Braga (POR) 1-2 Elfsborg (SWE) / Elfsborg 2-0 Braga
Aberdeen (SCO) 1-5 Sigma Olomouc (CZE) / Sigma Olomouc 3-0 Aberdeen
Rabotnicki (MKD) 3-4 Odense (DEN) / Odense 3-0 Rabotnicki
Sevojno (SRB) 0-2 Lille (FRA) / Lille 2-0 Sevojno
Petrovac (MNE) 1-2 Sturm Graz (AUT) / Sturm Graz 5-0 Petrovac
Fenerbahce (TUR) 5-1 Budapest Honved (HUN) / Budapest Honved 1-1 Fenerbahce
Bnei Yehuda Tel-Aviv (ISR) 1-0 Pacos Ferreira (POR) / Pacos Ferreira 0-1 Bnei Yehuda Tel-Aviv
Club Brugge (BEL) 3-2 Lahti (FIN) / Lahti 1-1 Club Brugge
Athletic Bilbao (ESP) 0-1 Young Boys (SUI) / Young Boys 1-2a Athletic Bilbao
Reykjavik (ISL) 2-2 Basel (SUI) / Basel 3-1 Reykjavik
Maccabi Netanya (ISR) 1-4 Galatasaray (TUR) / Galatasaray 6-0 Maccabi Netanya
Dinamo Tbilisi (GEO) 2-0 Crvena Zvezda (SRB) / Crvena Zvezda 5-2 Dinamo Tbilisi
Polonia Warszawa (POL) 0-1 NAC Breda (NED) / NAC Breda 3-1 Polonia Warszawa
Vetra (LTU) 0-3 Fulham (ENG) / Fulham 3-0 Vetra