Former Italy coach Roberto Donadoni has taken charge of Napoli after the club decided to dismiss Edoardo Reja following a nine-game winless streak in Serie A.
Donadoni, who previously coached Atalanta and Livorno, has been out of football since Italy's exit at the UEFA Euro 2008 tournament at the quarter-final stage last summer.
"Napoli announce that they have removed Eduardo Reja from his position as first team coach and handed the reins to Roberto Donadoni," read an official club statement.
"The club made this decision with great suffering, considering the crucial role Reja has played during the last five years which have seen Napoli go from Serie C to Serie A and then to the UEFA Cup.
"Naturally the club would like to thank Reja with deep gratitude for his great professional performance during all these winning years."
Reja led Napoli, backed by a huge fan base and the money of film producer Aurelio De Laurentiis, from Serie C1 to Serie A in just two seasons between 2005 and 2007, and after a bright start to this season the Partenopei were at one stage sitting pretty at the top of Serie A.
However, they have not won since the visit of Catania to the Stadio San Paolo on 11 January, earning just two points in nine league games, culminating in Sunday's 2-0 home defeat by Lazio, leaving them in the bottom half of the table.
Donadoni, a three-time European Cup winner as an AC Milan player and capped 63 times for the national team, has agreed a contract until 2011 and will begin his reign at bottom-of-the-table Reggina on Sunday.