Atalanta were humbled 1-0 at home by third division neighbours Lumezzane to go out of the Coppa Italia fourth round, but Napoli avoided an upset and Palermo easily progressed.
Antonio Conte's Atalanta are currently struggling in Serie A, sitting 17th in the table, and a 1-0 defeat to third-tier outfit Lumezzane will only increase the misery.
Michele Marconi, on loan at Lumezzane from the Bergamo outfit, embarrassed his parent club with the only goal after 19 minutes to set up a last 16 tie with Udinese.
Palermo will meet holders Lazio after defeating Serie B side Reggina 4-1 at home in former Lazio boss Delio Rossi's first game since succeeding Walter Zenga as coach earlier this week.
A penalty from Fabrizio Miccoli on the half-hour had given the Sicilians control, but Sergio Volpi managed to cancel the lead out three minutes into the second half.
Edinson Cavani's strike shortly before the hour mark put Palermo back in front before Igor Budan netted twice in the space of five minutes to crush any hope of a surprise result for the struggling visitors.
In the night's other game, Napoli were 1-0 winners over Cittadella as Mariano Bogliacino's 27th minute goal proved enough against Serie B opponents, who had Andrea Pisani sent off late on.
The slender win secures a fifth round encounter with rivals Juventus.
The remaining fourth round ties will be completed next week.
Fourth Round Results
Wednesday 25 November 2009
Chievo 2-0 Frosinone
Siena 0-2 Novara
Thursday 26 November 2009
Atalanta 0-1 Lumezzane
Napoli 1-0 Cittadella
Palermo 4-1 Reggina
Fourth Round Fixtures
Tuesday 1 December 2009
Triestina v Sassuolo (1900)
Sampdoria v Livorno (1930)
Wednesday 2 December 2009
Catania v Empoli (1400)
Fifth Round Draw
10, 15 December 2009, 13 January 2010
Fiorentina v Chievo
Lazio v Palermo
Juventus v Napoli
Inter v Sampdoria/Livorno
Milan v Novara
Udinese v Lumezzane
Roma v Triestina/Sassuolo
Genoa v Catania/Empoli
* All kick-off times listed are UK time (+1 for Italy/CET). Times, dates and fixtures are subject to change.
Coppa Italia Fourth Round Reviews
[25 Nov 2009] - [26 Nov 2009] - [1 Dec 2009] - [2 Dec 2009]
Source: Sky Sports