Italy captain Fabio Cannavaro has failed a dope test after taking a medicine that contained the banned substance cortisone.
The 2006 World Player of the Year was allegedly stung by a wasp and took a medicine that contained the banned substance, which is often used to suppress pain.
The veteran defender requested an exemption on the grounds of having taken a medication in the case of an emergency but his request was missing a document and while awaiting a decision he was subjected to an anti-doping test, which returned a positive result.
Sources close to his club Juventus have claimed he took nothing more than an anti-allergy medicine.
Cannavaro had been expected to join the Italy squad this weekend for next Wednesday's World Cup qualifier against Cyprus in Parma. He is suspended for Saturday's match against the Republic of Ireland in Dublin, when a draw will suffice to book the Azzurri's place in South Africa next year.
He is due to be interviewed by the Italian Olympic Committee's (CONI) anti-doping prosecutor Etorre Torri on Friday morning in Turin.
CONI released a statement on its website explaining the circumstances of the positive test without revealing if any action will be taken against the player.
"After an Italian player made a request for an exemption for therapeutic reasons for medicine given in an emergency, CONI's Therapeutic Exemption Committee requested via registered letter that the Emergency Room doctor's certificate be added to the documentation sent," read a statement from CONI.
"In the meantime, the athlete was subjected to an anti-doping test and the result was positive."