AC Milan host Bologna on Sunday looking to pick up where they left off in midweek.
The Rossoneri got their UEFA Champions League campaign off to a great start with a 2-1 win over Marseille in France.
Italian veteran striker Pippo Inzaghi continued his impressive European record by scoring twice to hand the Rossoneri a deserved triumph.
The result was important to lift the spirits of the team after last weekend's goalless draw at Livorno dropped Leonardo's side to 10th in the standings, five points behind leaders Juventus, Genoa and Sampdoria.
Juventus were held to a 1-1 draw in midweek by Bordeaux and travel to Leghorn on Saturday evening to meet Livorno determined to maintain their perfect start in the league.
Genoa and Sampdoria want to continue to delight football fans in the Italian Riviera by claiming their fourth consecutive triumphs this weekend.
The Grifoni, who kicked off their UEFA Europa League campaign with a 2-0 win over Slavia Prague on Thursday, brushed aside Napoli 4-1 in the last round and take on Chievo in Verona on Sunday.
Luigi Del Neri's Sampdoria welcome Siena to Genoa.
Inter held defending European champions Barcelona to a goalless draw at the San Siro in midweek and expect to claim all points when they make the journey to Sardinia to meet Cagliari.
The Nerazzurri trail two points behind the Serie A leaders after three games played.
Fiorentina will have Romanian striker Adrian Mutu available for Sunday night's big clash at Roma.
Mutu, who returned to play in Wednesday's 1-0 defeat at Lyon, missed the last two league encounters with a muscular injury but is expected to lead the Viola's attack at the Stadio Olimpico.
Roma were beaten 2-0 at Basel in the Europa League in midweek but Claudio Ranieri's new side will hope to build on last week's win over Siena.
Napoli coach Roberto Donadoni will be under pressure to take a positive result against Udinese in Saturday's early game after his team's disappointing display at Genoa last weekend.
The 4-1 humiliation marked the Partenopei's second defeat of the campaign.
Atalanta travel to Bari hoping to kick-start their campaign having failed to take a point in their last three games.
Catania went down 4-2 at Udinese in the last round and will seek their first points of the campaign when they host a Lazio who crashed to a late 2-1 defeat to Salzburg in the Europa League on Thursday.
Parma go into Sunday's clash against Palermo looking to bounce back from their first defeat of the campaign, a 2-0 loss at Inter last weekend.