Bologna have parted company with coach Sinisa Mihajlovic following their 4-1 home defeat against Siena on Saturday and have appointed Giuseppe Papadopulo in his place.
The former Roma, Sampdoria, Lazio and Inter defender had replaced Daniele Arrigoni in November with the seven-time Italian champions second from bottom in Serie A.
"Bologna have sacked first-team coach Sinisa Mihajlovic," read an official club statement. "The club wishes him great thanks for his involvement and professionalism.
"The technical managing has been assigned to Giuseppe Papadopulo, who will be unveiled on Wednesday."
It was the 40-year-old Mihajlovic's first job as head coach after assisting Roberto Mancini at Inter last season, but after a promising start the Rossoblu have lost four straight league matches and six of their last seven to slip back into the relegation zone, one point from safety.
Papadopulo, 61, made his name at Siena, leading the Tuscan club to promotion to Serie A in 2002. He has also coached Lazio and Palermo, who he will face in his first match in charge of Bologna on Sunday.
He left Lecce last summer despite leading them back into the Italian top flight.