Adriano will miss two Serie A matches after his ban for diving was confirmed by the FIGC's Disciplinary Commission.
Inter had lodged an emergency appeal against the suspension, hoping to have the striker back in action for the games against Siena this Sunday and Empoli next weekend.
The Disciplinary Commission rejected the bid and confirmed that Adriano would be punished for his simulation at the San Siro on Wednesday.
The Brazilian was judged to have dived in order to earn Inter a penalty in the 3-1 defeat to Roma. Marco Materazzi had scored the spot-kick for a temporary equaliser.
The decision to ban Adriano infuriated Nerazzurri President Massimo Moratti who said, "The decision to suspend the player was true buffoonery. This is pure nonsense.
"There was no penalty and I was the first one to say so, but a two-match ban for being awarded a spot-kick is absurd."
Inter have announced they will continue their legal battle to clear Adriano. The club tonight released an official statement announcing that further legal action would be taken in the CAF Court of Appeal.
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